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Nemifitide Free Base

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Specification

Cat. No.

SMD1020

Related Diseases

Depression

Product Name

Nemifitide Free Base

Size

Customizable

Price

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Description

Nemifitide Free Base is a novel antidepressant drug with a pentapeptide structure similar to that of melanocyte-inhibiting factor and the amino acid sequence 4-F-Phe-4-OH-Pro-Arg-Gly-Trp-NH₂. It is under development by Tetragenex for the treatment of major depressive disorder.

CAS Number

173240-15-8 (free base)

Chemical Formula

C33H43FN10O6

Exact Mass

694.3351

Molecular Weight

694.77

Elemental Analysis

C, 57.05; H, 6.24; F, 2.73; N, 20.16; O, 13.82

Synonym

Nemifitide Free Base

IUPAC/Chemical Name

(2S,4R)-N-((S)-1-((2-(((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)amino)-5-guanidino-1-oxopentan-2-yl)-1-((S)-2-amino-3-(4-fluorophenyl)propanoyl)-4-hydroxypyrrolidine-2-carboxamide

InChi Key

SGXPTOACEHQGHL-RCNLLYRESA-N

InChi Code

InChI=1S/C33H43FN10O6/c34-20-9-7-18(8-10-20)12-23(35)32(50)44-17-21(45)14-27(44)31(49)43-25(6-3-11-39-33(37)38)30(48)41-16-28(46)42-26(29(36)47)13-19-15-40-24-5-2-1-4-22(19)24/h1-2,4-5,7-10,15,21,23,25-27,40,45H,3,6,11-14,16-17,35H2,(H2,36,47)(H,41,48)(H,42,46)(H,43,49)(H4,37,38,39)/t21-,23+,25+,26+,27+/m1/s1

SMILES Code

N[C@H](C(N1C[C@@H](C[C@H]1C(N[C@H](C(NCC(N[C@H](C(N)=O)Cc(c[nH]2)c3c2cccc3)=O)=O)CCCNC(N)=N)=O)O)=O)Cc4ccc(F)cc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.