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Napitane Mesylate

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Specification

Cat. No.

SMD1041

Related Diseases

Depression

Product Name

Napitane Mesylate

Size

Customizable

Price

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Description

Napitane Mesylate, also known as ABT-200 or A-75200, is a potent alpha 2-adrenoceptor antagonist. Napitane Mesylate binds to CA transporters in the central nervous system and blocks uptake. Napitane Mesylate also blocks norepinephrine uptake by inhibiting the norepinephrine transporter.

CAS Number

149189-73-1 (mesylate)

Chemical Formula

C23H29NO5S

Molecular Weight

431.547

Elemental Analysis

C, 64.01; H, 6.77; N, 3.25; O, 18.54; S, 7.43

Synonym

Napitane Mesylate; ABT-200; A-75200

IUPAC/Chemical Name

(1'R*,3R*)-3-Phenyl-1- [(1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate

InChi Key

IXLOGUKQFISQPX-APTPAJQOSA-N

InChi Code

InChI=1S/C22H25NO2.CH4O3S/c1-2-5-16(6-3-1)17-11-12-23(13-17)14-18-7-4-8-20-19(18)9-10-21-22(20)25-15-24-21;1-5(2,3)4/h1-3,5-6,9-10,17-18H,4,7-8,11-15H2;1H3,(H,2,3,4)/t17-,18-;/m0./s1

SMILES Code

CS(=O)(O)=O.N1(C[C@@H]2CCCC3=C2C=CC4=C3OCO4)C[C@@H](C5=CC=CC=C5)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.