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Napamezole

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Specification

Cat. No.

SMD306

Related Diseases

Anxiety

Related Diseases

Depression

Product Name

Napamezole

Size

Customizable

Price

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Description

Napamezole, also known as WIN-51181, is an α2 adrenergic receptor antagonist potentially for the treatment of major depressive disorder and anxiety. Napamezole reversed clonidine-induced decreased in twitch height in the electrically stimulated rat vas deferens. Napamezole also antagonized methoxamine-induced contractions (alpha-1) of the rat vas deferens with a Kb of 135 nM.

CAS Number

91524-14-0

Chemical Formula

C14H16N2

Exact Mass

212.1313

Molecular Weight

212.296

Elemental Analysis

C, 79.21; H, 7.60; N, 13.20

Synonym

Napamezole; WIN-51181; WIN 51181; WIN51181

IUPAC/Chemical Name

2-((3,4-dihydronaphthalen-2-yl)methyl)-4,5-dihydro-1H-imidazole

InChi Key

WETRBJOSGIDJHQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H16N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-4,9H,5-8,10H2,(H,15,16)

SMILES Code

C1(CC2=CC3=C(C=CC=C3)CC2)=NCCN1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.