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MPEP HCl

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Specification

Cat. No.

SMD308

Related Diseases

Anxiety

Related Diseases

Depression

Product Name

MPEP HCl

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g

Price

Inquiry

Availability

2 Weeks

Description

MPEP is a selective mGluR5 antagonist. MPEP reverses maze learning and PSD-95 deficits in Fmr1 knock-out mice. MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug.

CAS Number

219911-35-0 (HCl)

Chemical Formula

C14H12ClN

Molecular Weight

229.707

Elemental Analysis

C, 73.20; H, 5.27; Cl, 15.43; N, 6.10

Synonym

MPEP; MPEP HCl; MPEP hydrochloride.

IUPAC/Chemical Name

2-Methyl-6-(phenylethynyl)pyridine hydrochloride

InChi Key

PKDHDJBNEKXCBI-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H

SMILES Code

CC1=NC(C#CC2=CC=CC=C2)=CC=C1.[H]Cl

Appearance

Yellow solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.