Related Diseases
Bipolar Disorder
Related Diseases
Depression
Product Name
Moclobemide-d4
Size
1.0mg; 5.0mg; 10.0mg; 25.0mg
Description
Moclobemide-d4 is intended for use as an internal standard for the quantification of moclobemide by GC- or LC-MS. Moclobemide is a reversible inhibitor of monoamine oxidase A (MAO-A; Ki = 0.005 µM). It is selective for MAO-A over MAO-B (Ki = 1.08 µM). Chronic administration of moclobemide (15 mg/kg) decreases immobility in the forced swim test in rats. It increases time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic-like activity, when administered chronically at a dose of 20 mg/kg. Formulations containing moclobemide have been used in the treatment of major depressive disorder, bipolar disorder, and social anxiety.
Chemical Formula
C13H13D4ClN2O2
Molecular Weight
272.7654
Elemental Analysis
C, 57.24; H, 7.76; Cl, 13.00; N, 10.27; O, 11.73
Synonym
Moclobemide-d4; Moclobemide d4;
IUPAC/Chemical Name
4-chloro-N-(2-morpholinoethyl)benzamide-2,3,5,6-d4
InChi Key
YHXISWVBGDMDLQ-RHQRLBAQSA-N
InChi Code
InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)/i1D,2D,3D,4D
SMILES Code
ClC1=C(C([2H])=C(C([2H])=C1[2H])C(NCCN2CCOCC2)=O)[2H]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001