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MK-8998

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Specification

Cat. No.

SMD1580

Related Diseases

Schizophrenia

Product Name

MK-8998

Size

Customizable

Price

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Description

MK-8998 is a T type calcium channel antagonist potentially for the treatment of schizophrenia. MK-8998 was not effective in treating acutely psychotic inpatients with schizophrenia, as measured by PANSS score at week 4.

CAS Number

953778-58-0

Chemical Formula

C20H23F3N2O2

Exact Mass

380.1712

Molecular Weight

380.4112

Elemental Analysis

C, 63.15; H, 6.09; F, 14.98; N, 7.36; O, 8.41

Synonym

MK-8998; MK8998; MK 8998.

IUPAC/Chemical Name

(R)-2-(4-isopropylphenyl)-N-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide

InChi Key

IQIKXZMPPBEWAD-CQSZACIVSA-N

InChi Code

InChI=1S/C20H23F3N2O2/c1-13(2)16-6-4-15(5-7-16)10-19(26)25-14(3)18-9-8-17(11-24-18)27-12-20(21,22)23/h4-9,11,13-14H,10,12H2,1-3H3,(H,25,26)/t14-/m1/s1

SMILES Code

CC(C)C1=CC=C(CC(N[C@H](C)C2=NC=C(OCC(F)(F)F)C=C2)=O)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.