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MK-212 free base

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Specification

Cat. No.

SMD1569

Related Diseases

Schizophrenia

Related Diseases

Depression

Related Diseases

Anxiety

Product Name

MK-212 free base

Size

1.0g; 2.0g; 5.0g; 10.0g

Price

Inquiry

Availability

2 Weeks

Description

MK-212 is a 5HT2C-receptor agonist. A dose-dependent the effect of 5HT2C-receptor agonist MK-212 on mouse behavior was demonstrated. Intraperitoneal injection of MK-212 in high doses (0.5 and 1.0 mg/kg) increased blood level of corticosterone in mice and reduced their motor activity. In low doses of 0.1 and 0.2 mg/kg, the agonist reduced anxiety, but had no effect on motor activity. It is hypothesized that low doses of MK-212 exhibited anxiolytic activity in mice.

CAS Number

64022-27-1 (free base)

Chemical Formula

C8H11ClN4

Exact Mass

198.0672

Molecular Weight

198.654

Elemental Analysis

C, 48.37; H, 5.58; Cl, 17.85; N, 28.20

Synonym

MK212; MK 212; MK-212; MK-212 free base;

IUPAC/Chemical Name

2-chloro-6-(piperazin-1-yl)pyrazine

InChi Key

CJAWPFJGFFNXQI-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2

SMILES Code

ClC1=NC(N2CCNCC2)=CN=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.