Related Diseases
Schizophrenia
Size
10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg
Description
Mibampator, also known as LY-451395, is an AMPA receptor potentiator under development for agitation/aggression in Alzheimer's disease. Patients treated with LY451395 did not show a statistically significant separation from patients taking placebo on the Alzheimer's Disease Assessment Scale-Cognitive Subscale, the primary outcome measure.
Chemical Formula
C21H30N2O4S2
Elemental Analysis
C, 57.51; H, 6.89; N, 6.39; O, 14.59; S, 14.62
Synonym
LY-451395; LY 451395; LY451395; Mibampator
IUPAC/Chemical Name
(R)-N-(2-(4'-(2-(methylsulfonamido)ethyl)-[1,1'-biphenyl]-4-yl)propyl)propane-2-sulfonamide
InChi Key
ULRDYYKSPCRXAJ-KRWDZBQOSA-N
InChi Code
InChI=1S/C21H30N2O4S2/c1-16(2)29(26,27)23-15-17(3)19-9-11-21(12-10-19)20-7-5-18(6-8-20)13-14-22-28(4,24)25/h5-12,16-17,22-23H,13-15H2,1-4H3/t17-/m0/s1
SMILES Code
CC(S(=O)(NC[C@@H](C1=CC=C(C2=CC=C(CCNS(=O)(C)=O)C=C2)C=C1)C)=O)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001