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Metyrapone

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Specification

Cat. No.

SMD998

Related Diseases

Depression

Product Name

Metyrapone

Size

250.0mg; 500.0mg; 1.0g

Price

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Availability

2 Weeks

Description

Metyrapone is a drug used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). It blocks cortisol synthesis by reversibly inhibiting steroid 11β-hydroxylase. This stimulates ACTH secretion, which in turn increases plasma 11-deoxycortisol levels.

CAS Number

54-36-4

Chemical Formula

C14H14N2O

Exact Mass

226.1106

Molecular Weight

226.2738

Elemental Analysis

C, 74.31; H, 6.24; N, 12.38; O, 7.07

Synonym

Metyrapone, Metopirone, SU 4885, Methbipyranone, Methopyrapone

IUPAC/Chemical Name

2-methyl-1,2-dipyridin-3-ylpropan-1-one

InChi Key

FJLBFSROUSIWMA-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3

SMILES Code

CC(C1=CC=CN=C1)(C)C(C2=CC=CN=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.