Related Diseases
Depression
Product Name
MCI-225 hydrochloride hydrate
Description
MCI-225, also known as AA-10021; AA-10025; AA-10026; DDP-225, is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor potentially for the treatment of irritable. MCI-225 enhances attentional eye tracking in midpontine pretrigeminal preparation. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergic neuron and cerebral glucose hypometabolism.
CAS Number
476148-82-0 (HCl hydrate)
Chemical Formula
C17H20ClFN4OS
Molecular Weight
382.8824
Elemental Analysis
C, 53.33; H, 5.27; Cl, 9.26; F, 4.96; N, 14.63; O, 4.18; S, 8.37
Synonym
MCI-225 hydrochloride hydrate, MCI225; AA-10021; AA-10025; AA-10026; DDP-225; AA10021; AA10025; AA10026; DDP225.
IUPAC/Chemical Name
Thieno(2,3-d)pyrimidine, 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)-, monohydrochloride, monohydrate
InChi Key
SAURKKOJWIFYSR-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H17FN4S.ClH.H2O/c1-11-10-13-15(12-4-2-3-5-14(12)18)20-17(21-16(13)23-11)22-8-6-19-7-9-22;;/h2-5,10,19H,6-9H2,1H3;1H;1H2
SMILES Code
CC1=CC2=C(C3=CC=CC=C3F)N=C(N4CCNCC4)N=C2S1.[H]Cl.[H]O[H]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001