Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

MAO-A/5-HT2AR Inhibitor I14

Inquiry

Specification

Cat. No.

SMD1000

Related Diseases

Depression

Product Name

MAO-A/5-HT2AR Inhibitor I14

Size

Customizable

Price

Inquiry

Description

MAO-A/5-HT2AR Inhibitor I14 is a dual MAO-A and 5-HT2AR inhibitor with improved antidepressant activity. The MAO-A/5-HT2AR Inhibitor I14 has been found to be able to occupy the active cavity of 5-HT2AR and MAO-A with multiple hydrogen bonding forces and π–π stacking interaction. It has also led to a reduction in the expression of 5-HT2AR in the brain tissue of mice through the promotion of interstitial 5-HT levels, which ultimately increases the efficiency of the antidepressant effect.

CAS Number

N/A

Chemical Formula

C31H30FN3O2

Exact Mass

495.2322

Molecular Weight

495.6

Elemental Analysis

C, 75.13; H, 6.10; F, 3.83; N, 8.48; O, 6.46

Synonym

MAO-A/5-HT2AR Inhibitor I14; MAO-A/5-HT2AR Inhibitor-I14; MAO-A/5-HT2AR InhibitorI14; MAO-A/5-HT2AR-IN-I14;

IUPAC/Chemical Name

5-((5-(4-(2-Fluorophenyl)piperazin-1-yl)pentyl)oxy)-7H-dibenzo[de,h]quinolin-7-one

InChi Key

QMLRYAOQDOORLC-UHFFFAOYSA-N

InChi Code

InChI=1S/C31H30FN3O2/c32-27-10-4-5-11-28(27)35-17-15-34(16-18-35)14-6-1-7-19-37-23-20-22-12-13-33-30-24-8-2-3-9-25(24)31(36)26(21-23)29(22)30/h2-5,8-13,20-21H,1,6-7,14-19H2

SMILES Code

O=C(C1=CC=CC=C12)C3=CC(OCCCCCN4CCN(C5=CC=CC=C5F)CC4)=CC6=CC=NC2=C63

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.