Related Diseases
Schizophrenia
Description
LY-379,268 is a potent and selective agonist for the group II metabotropic glutamate receptors (mGluR2/3). LY-379,268 has sedative, neuroprotective, anti-addictive and anticonvulsant effects in animals, and blocks the effects of PCP and DOI, which has led to research as antipsychotic drugs for the treatment of schizophrenia in animals.
Elemental Analysis
C, 44.92; H, 4.85; N, 7.48; O, 42.74
Synonym
LY379268; LY 379268; LY-379268.
IUPAC/Chemical Name
(1S,2R,5R,6R)-2-amino-4-oxabicyclo[3.1.0]hexane-2,6-dicarboxylic acid
InChi Key
YASVRZWVUGJELU-MDASVERJSA-N
InChi Code
InChI=1S/C7H9NO5/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
SMILES Code
O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])OC1)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001