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Luzindole

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Specification

Cat. No.

SMD960

Related Diseases

Depression

Product Name

Luzindole

Size

25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

Inquiry

Availability

2 Weeks

Description

Luzindole, also known as N-0774, and N-acetyl-2-benzyltryptamine, is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells. Luzindole inhibits the transient outward K+ current in rat cerebellar granule cells. Luzindole suppresses experimental autoimmune encephalomyelitis.

CAS Number

117946-91-5 (free base)

Chemical Formula

C19H20N2O

Exact Mass

292.1576

Molecular Weight

292.382

Elemental Analysis

C, 78.05; H, 6.90; N, 9.58; O, 5.47

Synonym

Luzindole, N-0774, N0774, N 0774, N-acetyl-2-benzyltryptamine

IUPAC/Chemical Name

N-Acetyl-2-benzyltryptamine

InChi Key

WVVXBPKOIZGVNS-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)

SMILES Code

O=C(NCCC1=C(CC2=CC=CC=C2)NC3=CC=CC=C13)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.