Related Diseases
Depression
Size
25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g
Description
Luzindole, also known as N-0774, and N-acetyl-2-benzyltryptamine, is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells. Luzindole inhibits the transient outward K+ current in rat cerebellar granule cells. Luzindole suppresses experimental autoimmune encephalomyelitis.
CAS Number
117946-91-5 (free base)
Chemical Formula
C19H20N2O
Elemental Analysis
C, 78.05; H, 6.90; N, 9.58; O, 5.47
Synonym
Luzindole, N-0774, N0774, N 0774, N-acetyl-2-benzyltryptamine
IUPAC/Chemical Name
N-Acetyl-2-benzyltryptamine
InChi Key
WVVXBPKOIZGVNS-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
SMILES Code
O=C(NCCC1=C(CC2=CC=CC=C2)NC3=CC=CC=C13)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001