Related Diseases
Insomnia
Related Diseases
Bipolar Disorder
Product Name
Lurasidone HCl
Size
1.0g; 2.0g; 5.0g; 10.0g; 20.0g; 50.0g; Click to view more sizes and prices
Description
Lurasidone HCl, also known as SM-13496, is an atypical antipsychotic drug. In the USA since 2013, it is also approved for the treatment of depressive episodes associated with bipolar I disorder as well as bipolar II disorder in adults when used alone or in combination with lithium, valproate, or lamotrigine. Lurasidone may be useful for treating the cognitive and memory deficits seen in schizophrenia. Lurasidone has activity at several serotonin receptors that are involved in learning and memory.
CAS Number
367514-88-3 (HCl)
Chemical Formula
C28H37ClN4O2S
Elemental Analysis
C, 63.56; H, 7.05; Cl, 6.70; N, 10.59; O, 6.05; S, 6.06
Synonym
SM-13496; SM 13496; SM13496; Lurasidone HCl. trade name Latuda.
IUPAC/Chemical Name
(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
InChi Key
NEKCRUIRPWNMLK-SCIYSFAVSA-N
InChi Code
InChI=1S/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/m0./s1
SMILES Code
O=C1N(C[C@H]2[C@H](CN3CCN(C4=NSC5=C4C=CC=C5)CC3)CCCC2)C([C@]6([H])[C@@](C7)([H])CC[C@@]7([H])[C@]16[H])=O.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001