Related Diseases
Schizophrenia
Description
Lu AF58801 is a selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors.
Chemical Formula
C20H23NO3
Elemental Analysis
C, 73.82; H, 7.12; N, 4.30; O, 14.75
Synonym
Lu AF58801; Lu-AF58801; LuAF58801; AF58801; AF-58801; AF 58801;
IUPAC/Chemical Name
(1S,2S)-2-Phenyl-cyclopropanecarboxylic acid [alpha(R)-(4-ethoxy-phenyl)-2-hydroxy-ethyl]-amide
InChi Key
UIVKAFXVMUZVHS-QYZOEREBSA-N
InChi Code
InChI=1S/C20H23NO3/c1-2-24-16-10-8-15(9-11-16)19(13-22)21-20(23)18-12-17(18)14-6-4-3-5-7-14/h3-11,17-19,22H,2,12-13H2,1H3,(H,21,23)/t17-,18+,19+/m1/s1
SMILES Code
O=C([C@@H]1[C@@H](C2=CC=CC=C2)C1)N[C@H](C3=CC=C(OCC)C=C3)CO
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.03.00