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Lofepramine

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Specification

Cat. No.

SMD968

Related Diseases

Depression

Product Name

Lofepramine

Size

50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g

Price

Inquiry

Availability

2 Weeks

Description

Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535). Lofepramine produces inhibition of liver tryptophan pyrollase activity in vitro.

CAS Number

23047-25-8

Chemical Formula

C26H27ClN2O

Exact Mass

418.1812

Molecular Weight

418.965

Elemental Analysis

C, 74.54; H, 6.50; Cl, 8.46; N, 6.69; O, 3.82

Synonym

Lofepramine; HSDB 7184; Amplit; LEO 640; Lofepraminum; Lopramine;

IUPAC/Chemical Name

4'-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon

InChi Key

SAPNXPWPAUFAJU-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3

SMILES Code

O=C(C1=CC=C(Cl)C=C1)CN(CCCN2C3=CC=CC=C3CCC4=CC=CC=C42)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.