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Lofepramine hydrochloride

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Specification

Cat. No.

SMD970

Related Diseases

Depression

Product Name

Lofepramine hydrochloride

Size

50.0mg; 250.0mg; 1.0g

Price

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Availability

2 Weeks

Description

Lofepramine is an antidepressant; serotonin and norepinephrine re-uptake inhibitor (SNRI). A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE. Lofepramine is a third generation tricyclic antidepressant utilized throughout Europe and Japan for the treatment of major depression.

CAS Number

26786-32-3

Chemical Formula

C26H28Cl2N2O

Exact Mass

454.1579

Molecular Weight

455.423

Elemental Analysis

C, 68.57; H, 6.20; Cl, 15.57; N, 6.15; O, 3.51

Synonym

Lofepramine hydrochloride; DB-2182; WHR 2908A; WHR-2908A;

IUPAC/Chemical Name

4'-Chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenone monohydrochloride

InChi Key

ZWZIQPOLMDPIQM-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H27ClN2O.ClH/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29;/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3;1H

SMILES Code

O=C(C1=CC=C(Cl)C=C1)CN(CCCN2C3=CC=CC=C3CCC4=CC=CC=C42)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.