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Lobeline

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Specification

Cat. No.

SMD938

Related Diseases

Depression

Product Name

Lobeline

Size

5.0mg

Price

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Availability

2 Weeks

Description

Lobeline, also known as C-07475, is a dopamine receptor modulator potentially for the treatment of Tourette's syndrome and attention. Lobeline improves acute lung injury via nuclear factor-κB-signaling pathway and oxidative stress. Lobeline shows protective effects against MPTP-induced dopaminergic neuron death and attenuates behavior deficits in animals.

CAS Number

90-69-7

Chemical Formula

C22H27NO2

Exact Mass

337.2042

Molecular Weight

337.463

Elemental Analysis

C, 78.30; H, 8.06; N, 4.15; O, 9.48

Synonym

Lobeline; C-07475; C 07475; C07475; 8,10-Diphenyllobelionol.

IUPAC/Chemical Name

2-((2S,6R)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one

InChi Key

MXYUKLILVYORSK-HKBOAZHASA-N

InChi Code

InChI=1S/C22H27NO2/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18/h2-7,9-12,19-21,24H,8,13-16H2,1H3/t19-,20+,21+/m1/s1

SMILES Code

CN1[C@H](CC(C2=CC=CC=C2)=O)CCC[C@@H]1C[C@H](O)C3=CC=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.