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Lifarizine

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Specification

Cat. No.

SMD967

Related Diseases

Depression

Product Name

Lifarizine

Size

Customizable

Price

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Description

Lifarizine, also known as RS-87476, is a calcium and sodium channel antagonist potentially for the treatment of stroke. Lifarizine (RS-87476) showed neuroprotective efficacy in a simplified rat survival model of 2 vessel occlusion. The effects of lifarizine on intracellular Ca2+ and glutamate exocytosis may contribute to its neuroprotective action.

CAS Number

119514-66-8

Chemical Formula

C29H32N4

Exact Mass

436.2627

Molecular Weight

436.603

Elemental Analysis

C, 79.78; H, 7.39; N, 12.83

Synonym

Lifarizine; RS-87476; RS 87476; RS87476; RS 87476-000; RS-87476-000.

IUPAC/Chemical Name

1-(Diphenylmethyl)-4-((5-methyl-2-p-tolylimidazol-4-yl)methyl)piperazine

InChi Key

HTDFEXRUDGWNHA-UHFFFAOYSA-N

InChi Code

InChI=1S/C29H32N4/c1-22-13-15-26(16-14-22)29-30-23(2)27(31-29)21-32-17-19-33(20-18-32)28(24-9-5-3-6-10-24)25-11-7-4-8-12-25/h3-16,28H,17-21H2,1-2H3,(H,30,31)

SMILES Code

CC1=CC=C(C2=NC(CN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)=C(C)N2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.