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L 741742 free base

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Specification

Cat. No.

SMD250

Related Diseases

Anxiety

Product Name

L 741742 free base

Size

Customizable

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Description

L 741742 (free base) is a potent and highly selective D4 dopamine receptor antagonist, with Ki values of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.

CAS Number

156337-32-5 (free base)

Chemical Formula

C23H25ClN2O

Exact Mass

380.1655

Molecular Weight

380.91

Elemental Analysis

C, 72.52; H, 6.62; Cl, 9.31; N, 7.35; O, 4.20

Synonym

L 741742 (free base); L 741742; L-741742; L741742; L-741,742; L 741,742; L741,742;

IUPAC/Chemical Name

5-(4-chlorophenyl)-4-methyl-3-(1-phenethylpiperidin-4-yl)isoxazole

InChi Key

QDMAKDIDFJTXEL-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H25ClN2O/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3

SMILES Code

CC1=C(C2=CC=C(Cl)C=C2)ON=C1C3CCN(CCC4=CC=CC=C4)CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.