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JTC-801 HCl

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Specification

Cat. No.

SMD259

Related Diseases

Anxiety

Product Name

JTC-801 HCl

Size

10.0mg; 25.0mg; 50.0mg; 100.0mg

Price

Inquiry

Availability

2 Weeks

Description

JTC-801 is an opioid analgesic drug used in scientific research. JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor. The noiciceptin receptor has complex effects which are involved in many processes involved in pain and inflammation responses, and activation of this receptor can either increase or reduce pain depending on dose. Drugs acting at the noiciceptin receptor may influence the effects of traditional analgesics such as NSAIDs, μ-opioid agonists, and cannabinoids. JTC-801 is an orally active drug that blocks the nociceptin receptor and produces analgesic effects in a variety of animal studies, and is particularly useful for neuropathic pain and allodynia associated with nerve injury.

CAS Number

244218-51-7 (free base).

Chemical Formula

C26H26ClN3O2

Molecular Weight

447.963

Elemental Analysis

C, 69.71; H, 5.85; Cl, 7.91; N, 9.38; O, 7.14

Synonym

JTC-801; JTC 801; JTC801; JTC-801 HCl.

IUPAC/Chemical Name

N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide hydrochloride

InChi Key

NQLIYKXNAXKMBL-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H

SMILES Code

O=C(NC1=CC=C2N=C(C)C=C(N)C2=C1)C3=CC=CC=C3COC4=CC=C(CC)C=C4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.