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JNJ-39393406

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Specification

Cat. No.

SMD1521

Related Diseases

Schizophrenia

Product Name

JNJ-39393406

Size

Customizable

Price

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Description

JNJ-39393406 is an alpha7 nicotinic acetylcholine receptor positive allosteric modulator. JNJ-39393406 plays a key role in inflammatory processes, and is thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease.

CAS Number

953428-73-4

Chemical Formula

C19H18F2N6O3

Exact Mass

416.14084

Molecular Weight

416.38

Elemental Analysis

C, 54.81; H, 4.36; F, 9.13; N, 20.18; O, 11.53

Synonym

JNJ-39393406; JNJ 39393406; JNJ39393406.

IUPAC/Chemical Name

1H-1,2,4-Triazole-1-propanamide, 3-((2,2-difluoro-1,3-benzodioxol-5-yl)amino)-N,N-dimethyl-5-(4-pyridinyl)-

InChi Key

IURMHZBQEYNQOH-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H18F2N6O3/c1-26(2)16(28)7-10-27-17(12-5-8-22-9-6-12)24-18(25-27)23-13-3-4-14-15(11-13)30-19(20,21)29-14/h3-6,8-9,11H,7,10H2,1-2H3,(H,23,25)

SMILES Code

O=C(N(C)C)CCN1N=C(NC2=CC=C(OC(F)(F)O3)C3=C2)N=C1C4=CC=NC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.