Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

JNJ-37822681

Inquiry

Specification

Cat. No.

SMD539

Related Diseases

Bipolar Disorder

Related Diseases

Schizophrenia

Product Name

JNJ-37822681

Size

Customizable

Price

Inquiry

Description

JNJ-37822681 is a novel, potent, specific, centrally active, and fast-dissociating D(2) antagonist with optimal brain disposition. JNJ-37822681 is the first compound that allows the evaluation of the potential value of fast D(2) antagonism for the treatment of schizophrenia and bipolar disorder.

CAS Number

935776-74-2

Chemical Formula

C17H17F5N4

Exact Mass

372.13734

Molecular Weight

372.34

Elemental Analysis

C, 54.84; H, 4.60; F, 25.51; N, 15.05

Synonym

JNJ-37822681; JNJ 37822681; JNJ37822681.

IUPAC/Chemical Name

3-Pyridazinamine, N-(1-((3,4-difluorophenyl)methyl)-4-piperidinyl)-6-(trifluoromethyl)-

InChi Key

UVUYWJWYRLJHEN-UHFFFAOYSA-N

InChi Code

1S/C17H17F5N4/c18-13-2-1-11(9-14(13)19)10-26-7-5-12(6-8-26)23-16-4-3-15(24-25-16)17(20,21)22/h1-4,9,12H,5-8,10H2,(H,23,25)

SMILES Code

FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.