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JNJ-18038683 free base

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Specification

Cat. No.

SMD916

Related Diseases

Depression

Product Name

JNJ-18038683 free base

Size

Customizable

Price

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Description

JNJ-18038683 is a 5-HT7 receptor antagonist which has been shown to be effective in models of depression and to increase the latency to rapid eye movement (REM) sleep and decrease REM duration. JNJ-18038683 enhanced serotonin transmission, antidepressant-like behavior, and REM sleep suppression induced by citalopram in rodents.

CAS Number

851373-91-6 (free base)

Chemical Formula

C20H20ClN3

Exact Mass

337.1346

Molecular Weight

337.85

Elemental Analysis

C, 71.10; H, 5.97; Cl, 10.49; N, 12.44

Synonym

JNJ-18038683; JNJ 18038683; JNJ18038683.

IUPAC/Chemical Name

3-(4-chlorophenyl)-1-(phenylmethyl)-5,6,7,8-tetrahydro-4H-pyrazolo[5,4-d]azepine

InChi Key

UKJPMZGILXATGT-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H20ClN3/c21-17-8-6-16(7-9-17)20-18-10-12-22-13-11-19(18)24(23-20)14-15-4-2-1-3-5-15/h1-9,22H,10-14H2

SMILES Code

ClC1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2CCNCC4)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.