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JNJ-10181457 dihydrochloride

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Specification

Cat. No.

SMD264

Related Diseases

Anxiety

Product Name

JNJ-10181457 dihydrochloride

Size

1.0mg; 5.0mg

Price

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Availability

2 Weeks

Description

JNJ-10181457 is an antagonist of histamine H3 receptors that increases extracellular norepinephrine and acetylcholine levels in the frontal cortex.

CAS Number

544707-20-2

Chemical Formula

C20H30Cl2N2O

Molecular Weight

385.373

Elemental Analysis

C, 62.33; H, 7.85; Cl, 18.40; N, 7.27; O, 4.15

Synonym

JNJ-10181457; RWJ 662733

IUPAC/Chemical Name

4-[[3-[4-(1-piperidinyl)-1-butyn-1-yl]phenyl]methyl]-morpholine, dihydrochloride

InChi Key

HDRIBIYPLKZUDQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H28N2O/c1-3-10-21(11-4-1)12-5-2-7-19-8-6-9-20(17-19)18-22-13-15-23-16-14-22/h6,8-9,17H,1,3-5,10-16,18H2

SMILES Code

N1(CC2=CC=CC(C#CCCN3CCCCC3)=C2)CCOCC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.