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Iptakalim Hydrochloride

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Specification

Cat. No.

SMD924

Related Diseases

Depression

Product Name

Iptakalim Hydrochloride

Size

Customizable

Price

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Description

Iptakalim is a K(ir) 6.1/SUR2B activator potentially for the treatment of pulmonary arterial hypertension. Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration. Iptakalim attenuates hypoxia-induced pulmonary arterial hypertension in rats by endothelial function protection. Iptakalim influences the proliferation and apoptosis of human pulmonary artery smooth muscle cells. Iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels.

CAS Number

642407-63-4 (HCl)

Chemical Formula

C9H22ClN

Molecular Weight

179.732

Elemental Analysis

C, 60.14; H, 12.34; Cl, 19.72; N, 7.79

Synonym

Iptakalim Hydrochloride

IUPAC/Chemical Name

N-(1-methylethyl)-1,1,2-trimethylpropylamine hydrochloride

InChi Key

RXNJQAYLNOXYKW-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H21N.ClH/c1-7(2)9(5,6)10-8(3)4;/h7-8,10H,1-6H3;1H

SMILES Code

CC(C)C(C)(C)NC(C)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.