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(–)-IHCH7041

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Specification

Cat. No.

SMD900

Related Diseases

Depression

Product Name

(–)-IHCH7041

Size

Customizable

Price

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Description

(–)-IHCH7041 is a optical rotation negative isomer of IHCH7041. (–)-IHCH7041 is a DRD2 partial agonist. (–)-IHCH7041 showed EC50 = 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment. (–)-IHCH7041 exhibited a inhibition constant (Ki) of 22.44 nM binding affinity at DRD2. (–)-IHCH7041 has antidepressant properties and reverses cognitive impairment.

CAS Number

2813335-07-6 (rotation negative)

Chemical Formula

C24H35N5O

Exact Mass

409.2842

Molecular Weight

409.578

Elemental Analysis

C, 70.38; H, 8.61; N, 17.10; O, 3.91

Synonym

(–)-IHCH7041; IHCH-7041; IHCH 7 041; IHCH7041;

IUPAC/Chemical Name

N′-[trans-4-[2-[(6aS)-4,6,6a,7,9,10-Hexahydro-8H-pyrazino[1,2-a]pyrrolo[4,3,2-de]quinolin-8-yl]ethyl]cyclohexyl]-N,N-dimethylurea

InChi Key

BRKGSTSSCHWCSJ-IHPCNDPISA-N

InChi Code

InChI=1S/C24H35N5O/c1-27(2)24(30)26-19-8-6-17(7-9-19)10-11-28-12-13-29-20(16-28)14-18-15-25-21-4-3-5-22(29)23(18)21/h3-5,15,17,19-20,25H,6-14,16H2,1-2H3,(H,26,30)/t17-,19-,20-/m0/s1

SMILES Code

O=C(N[C@H]1CC[C@H](CCN(CC2)C[C@@](C3)([H])N2C4=C5C3=CNC5=CC=C4)CC1)N(C)C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.