Ace Therapeutics helps clients identify biomarkers of susceptibility or risk for psychiatric disorders through our platform technology. These biomarkers may include genetic variants, protein expression patterns, metabolite levels, and more. Our one-stop biomarker discovery and validation service can help clients predict potential biomolecules that put individuals at risk of developing a psychiatric disorder, thereby guiding the precise diagnosis of psychiatric disorders and the development of personalized therapies.
Susceptibility or risk biomarkers are often used as indicators of risk for developing a disease or medical condition. A potential correlation between interleukin 6 (IL-6) and C-reactive protein (CRP) levels and the risk of developing SCZ has been demonstrated. Lower CRP levels and blockage of IL-6 signaling significantly increase the risk of SCZ and are considered potential susceptibility/risk biomarkers for this neuropsychiatric disorder. Thus, susceptibility or risk biomarkers can provide early warning before the onset of psychiatric symptoms, aiding in the development of early intervention and personalized prevention strategies.
Biomarker discovery and validation for psychiatric disorders is a complex and lengthy process, and Ace Therapeutics is working to achieve precision prevention of complex disorders by integrating information from multiple genetic susceptibility loci, as well as other potential biomarkers, thereby greatly improving the ability to predict, screen, and intervene in populations at high risk of psychiatric disorders prior to their onset.
The following are the key steps we consider in the development of biomarkers of susceptibility or risk for psychiatric disorders:
We combine multi-omics analytical techniques with high-throughput screening analyses to analyze biological samples to identify potential biomarkers associated with risk for psychiatric disorders.
We validated the potential biomarkers screened by in vitro and in vivo assays to determine their mechanisms of action in the development of psychiatric disorders.
Our professional data analysis services assess the predictive value and clinical application potential of biomarkers, thus providing valuable data for our clients' research.
Ace Therapeutics is committed to applying our expertise to help our clients advance in the research and development of biomarkers for susceptibility to psychiatric disorders. Please contact us for more details and we will be happy to assist you.
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