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ICI-118551 HCl

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Specification

Cat. No.

SMD217

Related Diseases

Anxiety

Product Name

ICI-118551 HCl

Size

10.0mg; 50.0mg

Price

Inquiry

Availability

2 Weeks

Description

ICI-118551, also known as ICI-118,551 and ICI 111581, is a selective beta-2 (β2) adrenergic receptor antagonist. ICI-118551 binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. The compound was developed by Imperial Chemical Industries, which was acquired by AkzoNobel in 2008. ICI-118,551 has no known therapeutic use in humans although it has been used widely in research to understand the action of the β2 adrenergic receptor, as few other specific antagonists for this receptor are known.

CAS Number

72795-01-8 (HCl)

Chemical Formula

C17H28ClNO2

Molecular Weight

313.87

Elemental Analysis

C, 65.06; H, 8.99; Cl, 11.29; N, 4.46; O, 10.19

Synonym

ICI 111581; ICI-111581; ICI111581; ICI118551; ICI 118551; ICI-118551; ICI118,551; ICI 118,551; ICI-118,551; ICI-118551 HCl.

IUPAC/Chemical Name

(2R,3R)-3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride

InChi Key

KBXMBGWSOLBOQM-CACIRBSMSA-N

InChi Code

InChI=1S/C17H27NO2.ClH/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17;/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3;1H/t13-,16+;/m1./s1

SMILES Code

C[C@@H](NC(C)C)[C@@H](O)COC1=CC=C(C)C2=C1CCC2.[H]Cl

Appearance

white to off-white solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.