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IC87201

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Specification

Cat. No.

SMD926

Related Diseases

Depression

Product Name

IC87201

Size

25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g

Price

Inquiry

Availability

2 Weeks

Description

IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain. IC87201 inhibited the in vitro binding of nNOS with PSD95, without inhibiting nNOS catalytic activity. nNOS-PSD95 interaction is important in maintaining hypersensitivity in acute and chronic pain. Disruption of the nNOS-PSD95 interaction provides a novel approach to obtain selective anti-hyperalgesic compounds.

CAS Number

866927-10-8

Chemical Formula

C13H10Cl2N4O

Exact Mass

308.0232

Molecular Weight

309.15

Elemental Analysis

C, 50.51; H, 3.26; Cl, 22.93; N, 18.12; O, 5.18

Synonym

IC87201; IC-87201; IC 87201.

IUPAC/Chemical Name

2-((1H-Benzo[d] [1,2,3]triazol-5-ylamino) methyl)-4,6-dichlorophenol

InChi Key

QEHVTUCLCBXQIC-UHFFFAOYSA-N

InChi Code

InChI=1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19)

SMILES Code

OC1=C(Cl)C=C(Cl)C=C1CNC2=CC=C(NN=N3)C3=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.