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Hydroxyzine free base

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Specification

Cat. No.

SMD223

Related Diseases

Anxiety

Product Name

Hydroxyzine free base

Size

100.0mg; 250.0mg; 500.0g

Price

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Availability

2 Weeks

Description

Hydroxyzine is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

CAS Number

68-88-2 (free base)

Chemical Formula

C21H27ClN2O2

Exact Mass

374.1761

Molecular Weight

374.91

Elemental Analysis

C, 67.28; H, 7.26; Cl, 9.46; N, 7.47; O, 8.53

Synonym

Hydroxyzine; NSC 169188; NSC-169188; NSC169188; U.C.B 4492;

IUPAC/Chemical Name

Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-

InChi Key

ZQDWXGKKHFNSQK-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2

SMILES Code

ClC1=CC=C(C(N2CCN(CCOCCO)CC2)C3=CC=CC=C3)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2933.59.9500

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.