Product Name
Hydroxyzine Dihydrochloride
Description
Hydroxyzine dihydrochloride is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
CAS Number
2192-20-3 (2HCl)
Chemical Formula
C21H29Cl3N2O2
Elemental Analysis
C, 56.32; H, 6.53; Cl, 23.75; N, 6.26; O, 7.15
Synonym
Hydroxyzine dihydrochloride; Hydroxyzine hydrochloride; Arcanax; Neurolax; Orgatrax; Pamoate, Hydroxyzine; Vistaril; NSC 169188; NSC-169188; NSC169188; U.C.B 4492;
IUPAC/Chemical Name
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride
InChi Key
ANOMHKZSQFYSBR-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
SMILES Code
ClC1=CC=C(C(N2CCN(CCOCCO)CC2)C3=CC=CC=C3)C=C1.[H]Cl.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001