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GW-803430

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Specification

Cat. No.

SMD885

Related Diseases

Depression

Product Name

GW-803430

Size

5.0mg; 25.0mg

Price

Inquiry

Availability

2 Weeks

Description

GW-803430 is a potent, orally active and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). GW-803430 displays antiobesity and antidepressant-like effects in rats and mice.

CAS Number

515141-51-2

Chemical Formula

C25H24ClN3O3S

Exact Mass

481.1227

Molecular Weight

481.995

Elemental Analysis

C, 62.30; H, 5.02; Cl, 7.35; N, 8.72; O, 9.96; S, 6.65

Synonym

GW-803430; GW 803430; GW803430.

IUPAC/Chemical Name

6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one

InChi Key

MWULMTACIBZPGN-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3

SMILES Code

O=C1C2=C(C=C(C3=CC=C(Cl)C=C3)S2)N=CN1C4=CC=C(OCCN5CCCC5)C(OC)=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.