GW-803430

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GW-803430

Specification
Cat. No.
SMD885
Related Diseases
Depression
Product Name
GW-803430
Size
5.0mg; 25.0mg
Price
Inquiry
Availability
2 Weeks
Description
GW-803430 is a potent, orally active and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). GW-803430 displays antiobesity and antidepressant-like effects in rats and mice.
CAS Number
515141-51-2
Chemical Formula
C25H24ClN3O3S
Exact Mass
481.1227
Molecular Weight
481.995
Elemental Analysis
C, 62.30; H, 5.02; Cl, 7.35; N, 8.72; O, 9.96; S, 6.65
Synonym
GW-803430; GW 803430; GW803430.
IUPAC/Chemical Name
6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one
InChi Key
MWULMTACIBZPGN-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3
SMILES Code
O=C1C2=C(C=C(C3=CC=C(Cl)C=C3)S2)N=CN1C4=CC=C(OCCN5CCCC5)C(OC)=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
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