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GSK163090

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Specification

Cat. No.

SMD849

Related Diseases

Depression

Product Name

GSK163090

Size

50.0mg; 100.0mg; 200.0mg; 500.0mg

Price

Inquiry

Availability

2 Weeks

Description

GSK163090 is Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. GSK163090 was found to combine potent in vivo activity with a strong preclinical developability profile, and on this basis it was selected as a drug candidate with the aim of assessing its potential as a fast-onset antidepressant/anxiolytic.

CAS Number

844903-58-8 (free base)

Chemical Formula

C25H29N5O

Exact Mass

415.2372

Molecular Weight

415.541

Elemental Analysis

C, 72.26; H, 7.03; N, 16.85; O, 3.85

Synonym

GSK163090; GSK-163090; GSK 163090.

IUPAC/Chemical Name

1-(3-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)phenyl)imidazolidin-2-one

InChi Key

ANGUXJDGJCHGOG-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H29N5O/c1-19-8-9-22-23(27-19)6-3-7-24(22)29-16-14-28(15-17-29)12-10-20-4-2-5-21(18-20)30-13-11-26-25(30)31/h2-9,18H,10-17H2,1H3,(H,26,31)

SMILES Code

O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.