Description
GR-73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).
Chemical Formula
C40H59N7O6S
Elemental Analysis
C, 62.72; H, 7.76; N, 12.80; O, 12.53; S, 4.19
Synonym
GR-73632; GR 73632; GR73632. delta-Aminovaleryl-9-pro-10-meleu-substance P (7-10)
IUPAC/Chemical Name
L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-
InChi Key
HQKPTSSZOJLFBZ-LJADHVKFSA-N
InChi Code
InChI=1S/C40H59N7O6S/c1-27(2)24-34(38(51)44-30(36(42)49)20-23-54-4)46(3)40(53)33-18-13-22-47(33)39(52)32(26-29-16-9-6-10-17-29)45-37(50)31(25-28-14-7-5-8-15-28)43-35(48)19-11-12-21-41/h5-10,14-17,27,30-34H,11-13,18-26,41H2,1-4H3,(H2,42,49)(H,43,48)(H,44,51)(H,45,50)/t30-,31-,32-,33-,34-/m0/s1
SMILES Code
CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)N(C([C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=CC=C3)NC(CCCCN)=O)=O)=O)CCC1)=O)C)=O
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001