Related Diseases
Anorexia
Description
Fpl 14294 is a novel CCK-8 agonist with potent intranasal anorectic activity in the rat.
Chemical Formula
C45H56N8O13S3
Elemental Analysis
C, 53.35; H, 5.57; N, 11.06; O, 20.53; S, 9.49
Synonym
Fpl 14294; Fpl-14294; Fpl14294;
IUPAC/Chemical Name
(5S,11S,14S,17S)-11-((1H-indol-3-yl)methyl)-5-amino-17-((N-methyl-N-(2-(4-(sulfooxy)phenyl)acetyl)-L-phenylalanyl)carbamoyl)-14-(2-(methylthio)ethyl)-6,9,12,15-tetraoxo-2-thia-7,10,13,16-tetraazanonadecan-19-oic acid
InChi Key
OHIZQRDUJDNZHS-WZUXKDABSA-N
InChi Code
InChI=1S/C45H56N8O13S3/c1-53(39(55)22-28-13-15-30(16-14-28)66-69(63,64)65)37(21-27-9-5-4-6-10-27)45(62)52-44(61)36(24-40(56)57)51-42(59)34(18-20-68-3)50-43(60)35(23-29-25-47-33-12-8-7-11-31(29)33)49-38(54)26-48-41(58)32(46)17-19-67-2/h4-16,25,32,34-37,47H,17-24,26,46H2,1-3H3,(H,48,58)(H,49,54)(H,50,60)(H,51,59)(H,56,57)(H,52,61,62)(H,63,64,65)/t32-,34-,35-,36-,37-/m0/s1
SMILES Code
O=C(NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](CC1=CNC2=C1C=CC=C2)NC(CNC([C@H](CCSC)N)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N(C(CC4=CC=C(OS(=O)(O)=O)C=C4)=O)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.03.00