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Ferulic Acid

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Specification

Cat. No.

SMD851

Related Diseases

Depression

Product Name

Ferulic Acid

Size

5.0g; 10.0g; 25.0g

Price

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Availability

2 Weeks

Description

Ferulic Acid is a fibroblast growth factor receptor 1 (FGFR1) inhibitor that has antioxidant, anti-inflammatory and anticancer properties. Ferulic acid increased monoamine neurotransmitter levels in the brain regions that are relative to mood disorders: the hippocampus and frontal cortex. The increased tend to serotonin and norepinephrine was also found in the hypothalamus after higher dose of ferulic acid treatment. Monoamine oxidase A (MAO-A) activity was inhibited in the frontal cortex and hippocampus when treatment with 40 and 80 mg/kg ferulic acid; while MAO-B activity did not change significantly. Ferulic acid provides neuroprotective effects against a middle cerebral artery occlusion (MCAO)-induced cerebral ischemia.

CAS Number

1135-24-6

Chemical Formula

C10H10O4

Exact Mass

194.0579

Molecular Weight

194.186

Elemental Analysis

C, 61.85; H, 5.19; O, 32.96

Synonym

Ferulic Acid, Methyl ferulate, trans-Ferulic acid, Coniferic acid, NSC 2821, NSC2821, NSC-2821

IUPAC/Chemical Name

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

InChi Key

KSEBMYQBYZTDHS-HWKANZROSA-N

InChi Code

InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+

SMILES Code

O=C(O)/C=C/C1=CC=C(O)C(OC)=C1

Appearance

White to light yellow crystalline powder.

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.