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Fenobam

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Specification

Cat. No.

SMD203

Related Diseases

Anxiety

Product Name

Fenobam

Size

Customizable

Price

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Description

Fenobam is a a potent and selective negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5. Fenobam displays inverse agonist properties; blocks mGluR5 constitutive activity in vitro (IC50 = 87 nM, slightly weaker than MPEP). Fenobam has been used as a lead compound for the development of a range of newer mGluR5 antagonists.

CAS Number

57653-26-6

Chemical Formula

C11H11ClN4O2

Exact Mass

266.0571

Molecular Weight

266.685

Elemental Analysis

C, 49.54; H, 4.16; Cl, 13.29; N, 21.01; O, 12.00

Synonym

Fenobam; NPL-2009; NPL2009; NPL 2009

IUPAC/Chemical Name

1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea

InChi Key

DWPQODZAOSWNHB-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)

SMILES Code

O=C(NC(N(C)C1)=NC1=O)NC2=CC=CC(Cl)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.