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Facinicline HCl

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Specification

Cat. No.

SMD1512

Related Diseases

Schizophrenia

Product Name

Facinicline HCl

Size

Customizable

Price

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Description

Facinicline, also known as RG-3487, R-3487 or MEM-3454, is a partial agonist of the nicotinic alpha-7 (α7) receptor that was being co-developed by Roche for the oral treatment of Alzheimer's.

CAS Number

677305-02-1(HCl)

Chemical Formula

C15H19ClN4O

Exact Mass

306.1247

Molecular Weight

306.794

Elemental Analysis

C, 58.73; H, 6.24; Cl, 11.55; N, 18.26; O, 5.21

Synonym

Facinicline HCl, Facinicline hydrochloride; RG-3487; RG 3487; RG3487; R-3487; R 3487; R3487; RO-5313534; RO 5313534; RO5313534; MEM3454; MEM 3454; MEM-3454;

IUPAC/Chemical Name

N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-1H-indazole-3-carboxamide hydrochloride

InChi Key

CMRLNEYJEPELSM-BTQNPOSSSA-N

InChi Code

InChI=1S/C15H18N4O.ClH/c20-15(14-11-3-1-2-4-12(11)17-18-14)16-13-9-19-7-5-10(13)6-8-19;/h1-4,10,13H,5-9H2,(H,16,20)(H,17,18);1H/t13-;/m1./s1

SMILES Code

O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.