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Facinicline free base

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Specification

Cat. No.

SMD1482

Related Diseases

Schizophrenia

Product Name

Facinicline free base

Size

Customizable

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Description

Facinicline, also known as RG-3487, R-3487 or MEM-3454, is a partial agonist of the nicotinic alpha-7 (α7) receptor that was being co-developed by Roche for the oral treatment of Alzheimer's.

CAS Number

677306-35-3 (free base)

Chemical Formula

C15H18N4O

Exact Mass

270.1481

Molecular Weight

270.336

Elemental Analysis

C, 66.64; H, 6.71; N, 20.73; O, 5.92

Synonym

Facinicline; RG-3487; RG 3487; RG3487; R-3487; R 3487; R3487; RO-5313534; RO 5313534; RO5313534; MEM3454; MEM 3454; MEM-3454;

IUPAC/Chemical Name

(S)-N-(quinuclidin-3-yl)-1H-indazole-3-carboxamide

InChi Key

TXCYUSKWBHUVEP-CYBMUJFWSA-N

InChi Code

InChI=1S/C15H18N4O/c20-15(14-11-3-1-2-4-12(11)17-18-14)16-13-9-19-7-5-10(13)6-8-19/h1-4,10,13H,5-9H2,(H,16,20)(H,17,18)/t13-/m1/s1

SMILES Code

C1CN2CCC1[C@@H](C2)NC(=O)C3=NNC4=CC=CC=C43

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.