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Fabomotizole HCl

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Specification

Cat. No.

SMD238

Related Diseases

Anxiety

Product Name

Fabomotizole HCl

Size

10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg

Price

Inquiry

Availability

2 Weeks

Description

Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors.

CAS Number

173352-39-1 (HCl)

Chemical Formula

C15H22ClN3O2S

Exact Mass

307.1354

Molecular Weight

343.87

Elemental Analysis

C, 52.39; H, 6.45; Cl, 10.31; N, 12.22; O, 9.31; S, 9.32

Synonym

CM-346; CM346; CM 346; Fabomotizole; Obenoxazine; Afobazol; Afobazole; Aphobazole; Afobazole HCl; Afobazole hydrochloride

IUPAC/Chemical Name

4-(2-((5-ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride

InChi Key

MYSRFAUFQZYTOV-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H21N3O2S.ClH/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18;/h3-4,11H,2,5-10H2,1H3,(H,16,17);1H

SMILES Code

CCOC1=CC=C2NC(SCCN3CCOCC3)=NC2=C1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.