Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Fabomotizole free base

Inquiry

Specification

Cat. No.

SMD218

Related Diseases

Anxiety

Product Name

Fabomotizole free base

Size

Customizable

Price

Inquiry

Description

Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors.

CAS Number

173352-21-1 (free base)

Chemical Formula

C15H21N3O2S

Exact Mass

307.1354

Molecular Weight

307.41

Elemental Analysis

C, 58.61; H, 6.89; N, 13.67; O, 10.41; S, 10.43

Synonym

Fabomotizole Free Base; Obenoxazine; Afobazol; Afobazole; Aphobazole; CM-346; CM346; CM 346;

IUPAC/Chemical Name

5-Ethoxy-2-((2-(morpholin-4-yl)ethyl)sulfanyl)-1H-benzimidazole

InChi Key

WWNUCVSRRUDYPP-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H21N3O2S/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18/h3-4,11H,2,5-10H2,1H3,(H,16,17)

SMILES Code

CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.