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Evodiamine

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Specification

Cat. No.

SMD818

Related Diseases

Depression

Product Name

Evodiamine

Size

100.0mg; 250.0mg

Price

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Availability

2 Weeks

Description

d-Evodiamine is a topoisomerase I and II inhibitor found in the fruit of Evodia rutaecarpa Bentham (Rutaceae). It displays a wide variety of biological activities, including enhancing TRAIL-induced apoptosis in bladder cancer cells, inducing cell cycle arrest in leukemia cells, improving glucose tolerance, and inhibiting viral replication of influenza virus.

CAS Number

518-17-2

Chemical Formula

C19H17N3O

Exact Mass

303.1372

Molecular Weight

303.36

Elemental Analysis

C, 75.23; H, 5.65; N, 13.85; O, 5.27

Synonym

Evodiamine; Q-100579; Q100579; Q 100579; SC-16015; SC16015; SC 16015

IUPAC/Chemical Name

(S)-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

InChi Key

TXDUTHBFYKGSAH-SFHVURJKSA-N

InChi Code

InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1

SMILES Code

O=C1N2[C@](C(NC3=C4C=CC=C3)=C4CC2)([H])N(C)C5=C1C=CC=C5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.