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Elzasonan citrate

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Specification

Cat. No.

SMD843

Related Diseases

Depression

Product Name

Elzasonan citrate

Size

Customizable

Price

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Description

Elzasonan citrate is a selective 5-HT1B and 5-HT1D receptor antagonist for the treatment of depression. By preferentially blocking 5-HT1B and 5-HT1D autoreceptors, Elzasonan is thought to enhance serotonergic innervations originating from the raphe nucleus, thereby improving signaling to limbic regions like the hippocampus and prefrontal cortex and ultimately resulting in antidepressant effects.

CAS Number

361343-20-6(Elzasonan Citrate) ; 220322-05-4 (Elzasonan hydrochloride)

Chemical Formula

C28H31Cl2N3O8S

Molecular Weight

640.53

Elemental Analysis

C, 52.50; H, 4.88; Cl, 11.07; N, 6.56; O, 19.98; S, 5.01

Synonym

Elzasonan citrate; CP-448,187-10;UNII-67JE11VN82; Elzasonan citrate [USAN].

IUPAC/Chemical Name

(2Z)-4-(3,4-dichlorphenyl)-2-(2-(4-methylpiperazin-1-yl)benzylidene)thiomorpholin-3-one citrate (1:1)

InChi Key

FIXQLYVNGQBUAP-UXTSPRGOSA-N

InChi Code

InChI=1S/C22H23Cl2N3OS.C6H8O7/c1-25-8-10-26(11-9-25)20-5-3-2-4-16(20)14-21-22(28)27(12-13-29-21)17-6-7-18(23)19(24)15-17;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-7,14-15H,8-13H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b21-14-;

SMILES Code

CN1CCN(CC1)c2ccccc2\C=C\3/SCCN(C3=O)c4ccc(Cl)c(Cl)c4.OC(=O)CC(O)(CC(=O)O)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.