Related Diseases
Depression
Description
Edivoxetine, also known as LY2216684, is is a selective norepinephrine reuptake inhibitor under development for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant treatment. It was in phase III clinical trials, in 2012, for major depressive disorder, but failed to get approval.
CAS Number
1194508-25-2 (free base)
Chemical Formula
C18H26FNO4
Molecular Weight
339.4074
Elemental Analysis
C, 63.70; H, 7.72; F, 5.60; N, 4.13; O, 18.86
Synonym
LY2216684; LY-2216684; LY 2216684; Edivoxetine
IUPAC/Chemical Name
(R)-2-(5-fluoro-2-methoxyphenyl)-1-((S)-morpholin-2-yl)-1-(tetrahydro-2H-pyran-4-yl)ethan-1-ol
InChi Key
CPBHSHYQQLFAPW-ZWKOTPCHSA-N
InChi Code
InChI=1S/C18H26FNO4/c1-22-16-3-2-15(19)10-13(16)11-18(21,14-4-7-23-8-5-14)17-12-20-6-9-24-17/h2-3,10,14,17,20-21H,4-9,11-12H2,1H3/t17-,18+/m0/s1
SMILES Code
O[C@@](C1CCOCC1)(CC2=CC(F)=CC=C2OC)[C@@H]3CNCCO3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001