Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

DSR-141562

Inquiry

Specification

Cat. No.

SMD1510

Related Diseases

Schizophrenia

Product Name

DSR-141562

Size

25.0mg; 50.0mg; 100.0mg; 200.0mg

Price

Inquiry

Availability

2 Weeks

Description

DSR-141562, also known as LMN75224 is a phosphodiesterase 1 inhibitors useful for treatment of neurological and psychiatric disorder. DSR-141562 exhibits Efficacies in Animal Models for Positive, Negative, and Cognitive Symptoms Associated with Schizophrenia. DSR-141562 has preferential selectivity for predominantly brain-expressed PDE1B over other PDE1 family members, and high selectivity for the PDE1 family over other PDE families and 65 other tested biologic targets.

CAS Number

2007975-22-4

Chemical Formula

C19H25F3N4O3

Exact Mass

414.1879

Molecular Weight

414.4292

Elemental Analysis

C, 55.07; H, 6.08; F, 13.75; N, 13.52; O, 11.58

Synonym

DSR-141562; DSR-141562; DSR141562; DSR141562; ; LMN75224; LMN-75224; LMN 75224;

IUPAC/Chemical Name

3-Methyl-7-(tetrahydro-2H-pyran-4-yl)-2-[[trans-4-(trifluoromethyl)cyclohexyl]methoxy]imidazo[5,1-f][1,2,4]triazin-4(3H)-one

InChi Key

LNELWUPBSLZUIQ-MQMHXKEQSA-N

InChi Code

InChI=1S/C19H25F3N4O3/c1-25-17(27)15-10-23-16(13-6-8-28-9-7-13)26(15)24-18(25)29-11-12-2-4-14(5-3-12)19(20,21)22/h10,12-14H,2-9,11H2,1H3/t12-,14-

SMILES Code

O=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.