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DOV-216303 free base

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Specification

Cat. No.

SMD831

Related Diseases

Depression

Product Name

DOV-216303 free base

Size

5.0mg; 25.0mg

Price

Inquiry

Availability

2 Weeks

Description

DOV-216303 free base is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats.

CAS Number

66504-40-3 (free base)

Chemical Formula

C11H11Cl2N

Exact Mass

227.0269

Molecular Weight

228.116

Elemental Analysis

C, 57.92; H, 4.86; Cl, 31.08; N, 6.14

Synonym

DOV-216303 free base; DOV 216,303 free base

IUPAC/Chemical Name

1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane

InChi Key

BSMNRYCSBFHEMQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H11Cl2N/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11/h1-3,8,14H,4-6H2

SMILES Code

ClC1=CC=C(C23CNCC2C3)C=C1Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.