Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Donepezil HCl

Inquiry

Specification

Cat. No.

SMD1505

Related Diseases

Schizophrenia

Product Name

Donepezil HCl

Size

200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g

Price

Inquiry

Availability

2 Weeks

Description

Donepezil HCl is a GSK3 and AChE inhibitor and potential σ1 receptor agonist used to treat Alzheimer's disease. It also improves learning and memory, downregulates expression of NR1 subuinit of NMDA receptors, decreases left ventricular end diastolic pressure, and increases left ventricular contractility.

CAS Number

120011-70-3 (HCl)

Chemical Formula

C24H30ClNO3

Molecular Weight

415.95

Elemental Analysis

C, 69.30; H, 7.27; Cl, 8.52; N, 3.37; O, 11.54

Synonym

Aricept; E-2020; E2020; E 2020; Donepezil HCl

IUPAC/Chemical Name

2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride

InChi Key

XWAIAVWHZJNZQQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

SMILES Code

O=C1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2933.39.9100

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.