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DH4

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Specification

Cat. No.

SMD800

Related Diseases

Depression

Product Name

DH4

Size

Customizable

Price

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Description

DH4 is a SERT inhibitor with IC50 = 0.58 nM. DH4 was discovered with a bioavailability of 83.28% in rats by replacing the nonbioavailable substructure of approved drug vilazodone. DH4 exhibits promising antidepression efficacy in animal experiments.

CAS Number

N/A

Chemical Formula

C26H24F2N6

Exact Mass

458.2

Molecular Weight

458.52

Elemental Analysis

C, 68.11; H, 5.28; F, 8.29; N, 18.33

Synonym

DH4; DH 4; DH-4

IUPAC/Chemical Name

3-(3-(4-(5-(2,4-difluorophenyl)pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile

InChi Key

MONCKXMZFAXBAZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H24F2N6/c27-21-4-5-22(24(28)13-21)20-16-31-26(32-17-20)34-10-8-33(9-11-34)7-1-2-19-15-30-25-6-3-18(14-29)12-23(19)25/h3-6,12-13,15-17,30H,1-2,7-11H2

SMILES Code

FC1=CC(F)=CC=C1C(C=N2)=CN=C2N(CC3)CCN3CCCC4=CNC5=CC=C(C#N)C=C54

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.