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DDPM-2571 HCl

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Specification

Cat. No.

SMD787

Related Diseases

Depression

Product Name

DDPM-2571 HCl

Size

Customizable

Price

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Description

DDPM-2571 is a highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties. DDPM-2571 was quickly distributed into the brain and was highly effective in the prevention of chemically-induced seizures (pentylenetetrazole and pilocarpine models) and 6-Hz convulsions. It demonstrated significant anxiolytic-like and antidepressant-like properties. DDPM-2571 had antinociceptive properties, both in the hot plate test and in the second phase of the formalin test.

CAS Number

1672672-26-2 (HCl)

Chemical Formula

C21H21Cl3N2O3

Molecular Weight

455.76

Elemental Analysis

C, 55.34; H, 4.64; Cl, 23.33; N, 6.15; O, 10.53

Synonym

DDPM-2571; DDPM-2571; DDPM-2571;

IUPAC/Chemical Name

(E)-1-(2-((((2',4'-dichloro-[1,1'-biphenyl]-2-yl)methylene)amino)oxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride

InChi Key

VSUXRUCFNHSXSI-KEJAMGHHSA-N

InChi Code

InChI=1S/C21H20Cl2N2O3.ClH/c22-17-7-8-19(20(23)12-17)18-6-2-1-4-15(18)13-24-28-11-10-25-9-3-5-16(14-25)21(26)27;/h1-2,4-8,12-13H,3,9-11,14H2,(H,26,27);1H/b24-13+;

SMILES Code

[H]Cl.OC(C1=CCCN(C1)CCO/N=C/C2=CC=CC=C2C3=C(Cl)C=C(Cl)C=C3)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.03.00

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.